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KMID : 1001020130110030116
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Korean Journal of Urological Oncology
2013 Volume.11 No. 3 p.116 ~ p.121
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Prostate-Specific Antigen Velocity as a Prognostic Tool in Localized Prostate Cancer
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Ham Won-Sik
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Abstract
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It has been reported that prostate-specific antigen (PSA) velocity (PSAV) is statistically associated with many prostate cancer outcomes, including those related to early detection. However, the clinical use of a marker should depend on clinical and statistical significance. Before PSAV is used to inform decisions such as whether to perform a biopsy, evidence should be clear that doing so would improve clinical outcome. Therefore, the use of PSAV as a marker in localized prostate cancer has sometimes been described as controversial. The purpose of this review is to introduce the conflicting opinions on the role of PSAV as a prognostic tool in localized prostate cancer and the usefulness of PSAV in real clinical practice.
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KEYWORD
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Prostate cancer, PSA velocity
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